With advent of sophisticated equipment we know much in life science, but in many aspects we understand little, consider unexplained phenomena as gift of nature. But nature cannot act in self styled spontaneous manner. It should obey certain defined physical rules. Simple classical chemical reactions failed to solve various natural puzzles. Nature keeps continuity in the formation of universe to tiny creatures up to smallest bacteria, virus or plasmid. Role of invisible force of self gravity in life science has been explored from terrestrial environment to journey through space microgravity and detailed in the book that may help to explore options, manage solutions and optimize results for better management of health and well being of living bodies. Potential binding energy of self gravity that acts universally on mass is the factor that keeps such continuity which can no longer be denied. Various century-old biological conundrums have been resolved through astrophysical principles on incorporation of concept on self gravity. Book is thus must reading for academicians, practitioners and students not only of all disciplines of life science but also to all branches of physical science.