This edited book focuses on strategic aspects of innovation in the context of resilience during and after a crisis. It investigates the strategies that firms utilize in order to cope with change especially in the competitive global marketplace. The book contends that, by design, entrepreneurship is strategic and innovative in every decision and action of a business. The goal of this book is to focus on the innovation and resilience behind these strategies in order to understand the business motivations. In particular, it focuses on the uncertainties initiated by the COVID-19 pandemic and highlights the growing research and practice experiences of resilient entrepreneurial businesses and innovations that continued to be stable and successful. The book thus extends current research on strategic entrepreneurship by integrating it with the field of resilience. This will help to bridge the gap between practice and theory with regard to strategic entrepreneurship. Furthermore, it enables an effective advancement of strategic entrepreneurship research in light of the COVID-19 pandemic.