Excerpt from The Retrospect of Medicine, Vol. 28: Being a Half-Yearly Journal, Containing a Retrospective View of Every Discovery and Practical Improvement in the Medical Sciences, July-December, 1853

The importance of ascertaining the remote originating cause of a dis case is great in proportion to the degree of doubt which there may be as to the precise nature of the local changes upon which the symptoms in any given case are supposed to depend.

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