This is the inaugural volume of a new book series entitled The Road to Scientific Success: Inspiring Life Stories of Prominent Researchers. Authoritative scientists such as Nobel Prize laureates Douglas D Osheroff and Herbert A Hauptman and US National Medal of Science recipients Paul Ching-Wu Chu and Eli Ruckenstein describe their life experiences in relation to how success was attained, how their careers were developed, how their research was steered, how priorities were set, and how difficulties were faced. These keys to success serve as a useful guide for anyone who is looking for advice on how to direct their career and conduct scientific research that will make an impact. The focus on the road to success (rather than scientific findings) and on personal experience aims to inspire and encourage readers to achieve greater success themselves.