Five generations after the Panamerican Revolution and the West is a very different place: Washington lies in ruin, Atlanta is under martial law, and Saskatchewan is used as an execution yard for political dissidents. Florida, Manhattan and California are under water. Everything south of Bolivia is hounded by cloned dire wolves as big as bears. Psychedelic breastmilk is the drug pandemic of the day. And in Haiti, an escaped enemy of the state plots an overthrow....

It's April of 2165, and the Republic of Panamerica is about to secure their interstellar Manifest Destiny. Five moons some twenty lightyears away have been discovered, yet as Panamerica goes through the final preparations to launch, Kayla Zimmer, a former inmate in a secret prison camp, has an agenda of her own.

El Presidente and his continental banana republic would have this day go down in history, and it's about the one thing Zimmer agrees with him on. This is their proudest moment, and the time for her revenge....