This issue of Interventional Cardiology Clinics will explore Updates in Percutaneous Coronary Intervention. Curated by the series Editor-in-Chief, Dr. Matthew J. Price, this issue will cover topics and advances in the field that are relevant for practicing clinicians. This issue is one of four selected each year by Dr. Price. The volume will include articles on: Current Concepts in Intraprocedural Pharmacology During PCI, Periprocedural Myocardial Infarction in Contemporary Practice, Newer Generation Metallic Stents: Design, Performance Characteristics, and Outcomes, Distal Transradial Access for Coronary Angiography and Intervention, Clinical Outcomes Data for iFR-guided PCI, Culprit-only or Complete Revascularization During STEMI in Patients with and Without Shock, Technical Approaches to Left Main Coronary Intervention: Contemporary Best Practices, Robotic Assisted Percutaneous Coronary Intervention, Orbital Atherectomy: A Comprehensive Review, and Percutaneous revascularization of spontaneous coronary artery dissection, among others.