During the last two decades management of venous ulcers has significantly improved. Most notably our understanding of genetics, pathophysiology and hemodynamic has evolved as well as novel diagnostic and treatment modalities of underlying incompetent venous system has been utilized at an exponential rate in management of chronic venous insufficiency patients. Venous Ulcers, Second Edition, provides evidence-based data pertinent to genetics, molecular and biochemical mechanisms that lead to development and progression of venous ulcers. It summarizes new findings and advances in the field in a clinically applicable way and serves as the most updated and comprehensive source for both the researchers and medical professionals who need more information on chronic venous insufficiency.