Featuring 143 clinical cases, 379 full-color photographs, and 857 case-based questions, the Wills Eye Review of Ophthalmology is an Internet-based interactive clinical review of ophthalmology and its subspecialties. Users are presented with a clinical photograph and scenario, and are then asked questions about differential diagnosis, testing, diagnosis, and treatment. The interactive Website recognizes typed responses, answers are followed with an explanation. This interactive case-based format fosters clinical decision-making and offers excellent preparation for written and oral board exams, recertification exams, and clinical practice.